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Index > Protein center > CST4(Gene name) > Human
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  • CST4 (Gene name),
  • Cystatin-S (Protein name ),  CYTS_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    CST4;
    Protein name:
    Cystatin-S;
    Alternative:
    Cystatin-SA-III;Cystatin-4;Salivary acidic protein 1;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    This protein strongly inhibits papain and ficin, partially inhibits stem bromelain and bovine cathepsin C, but does not inhibit porcine cathepsin B or clostripain. Papain is inhibited non-competitively.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    141
    Sequence:
    50:
    MARPLCTLLL | LMATLAGALA | SSSKEENRII | PGGIYDADLN | DEWVQRALHF | 
    100:
    AISEYNKATE | DEYYRRPLQV | LRAREQTFGG | VNYFFDVEVG | RTICTKSQPN | 
    141:
    LDTCAFHEQP | ELQKKQLCSF | EIYEVPWEDR | MSLVNSRCQE | A
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    KEGG:
    UniGene:
    MIM:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Cystatin-S
    Cat.:
    E13944r
    Price:
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human Cystatin-S
    Cat.:
    E13944h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Cystatin-S
    Cat.:
    U13944h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Cystatin-S
    Cat.:
    U13944r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Cystatin-S
    Cat.:
    P13944Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Cystatin-S
    Cat.:
    P13944Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Cystatin-S
    Monoclonal Antibody for Human Cystatin-S
    Protein for Human Cystatin-S
    Protein for Human Cystatin-S

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Human salivary cystatin S. Cloning, sequence analysis, hybridization in situ and immunocytochemistry."
      Bobek L.A. , Aguirre A. , Levine M.J.
      Biochem. J.278:627-635(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Submandibular gland.
    2. 2.
      "Characterization of two members (CST4 and CST5) of the cystatin gene family and molecular evolution of cystatin genes."
      Saitoh E. , Isemura S. , Sanada K. , Ohnishi K.
      Agents Actions38:340-348(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    3. 3.
      "Acquisition of complex patterns of differential expression in epithelial cell populations during the evolution of type 2 cystatin genes."
      Dickinson D.P. , Hewett-Emmett D. , Thiesse M.
      Submitted (2000-11) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    4. 4.
      "The DNA sequence and comparative analysis of human chromosome 20."
      Deloukas P. , Matthews L.H. , Ashurst J.L. , Burton J. , Gilbert J.G.R. , Jones M. , Stavrides G. , Almeida J.P. , Babbage A.K. , Bagguley C.L. , Bailey J. , Barlow K.F. , Bates K.N. , Beard L.M. , Beare D.M. , Beasley O.P. , Bird C.P. , Blakey S.E. , more...
      Nature414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Thyroid.
    6. 6.
      "Identification of a long form of cystatin from human saliva by rapid microbore HPLC mapping."
      Hawke D.H. , Yuan P.M. , Wilson K.J. , Hunkapiller M.W.
      Biochem. Biophys. Res. Commun.145:1248-1253(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 21-51
    7. 7.
      "Large-scale purification and characterization of the major phosphoproteins and mucins of human submandibular-sublingual saliva."
      Ramasubbu N. , Reddy M.S. , Bergey E.J. , Haraszthy G.G. , Soni S.-D. , Levine M.J.
      Biochem. J.280:341-352(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 21-55;PHOSPHORYLATION AT SER-23
      tissue: Saliva.
    8. 8.
      "Identification of full-sized forms of salivary (S-type) cystatins (cystatin SN, cystatin SA, cystatin S, and two phosphorylated forms of cystatin S) in human whole saliva and determination of phosphorylation sites of cystatin S."
      Isemura S. , Saitoh E. , Sanada K. , Minakata K.
      J. Biochem.110:648-654(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 21-36;PHOSPHORYLATION AT SER-21 AND SER-23
      tissue: Saliva.
    9. 9.
      "The effects of human salivary cystatins and statherin on hydroxyapatite crystallization."
      Johnsson M. , Richardson C.F. , Bergey E.J. , Levine M.J. , Nancollas G.H.
      Arch. Oral Biol.36:631-636(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 21-36;PHOSPHORYLATION AT SER-23
      tissue: Saliva.
    10. 10.
      "Isolation and amino acid sequence of SAP-1, an acidic protein of human whole saliva, and sequence homology with human gamma-trace."
      Isemura S. , Saitoh E. , Sanada K.
      J. Biochem.96:489-498(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 29-141
    11. 11.
      "Cystatin S: a cysteine proteinase inhibitor of human saliva."
      Isemura S. , Saitoh E. , Ito S. , Isemura M. , Sanada K.
      J. Biochem.96:1311-1314(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INHIBITOR SPECIFICITY
    12. 12.
      "Salivary cystatin SA-III, a potential precursor of the acquired enamel pellicle, is phosphorylated at both its amino- and carboxyl-terminal regions."
      Lamkin M.S. , Jensen J.L. , Setayesh M.R. , Troxler R.F. , Oppenheim F.G.
      Arch. Biochem. Biophys.288:664-670(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION
    13. 13.
      "Confident assignment of intact mass tags to human salivary cystatins using top-down Fourier-transform ion cyclotron resonance mass spectrometry."
      Ryan C.M. , Souda P. , Halgand F. , Wong D.T. , Loo J.A. , Faull K.F. , Whitelegge J.P.
      J. Am. Soc. Mass Spectrom.21:908-917(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-21 AND SER-23;DISULFIDE BONDS;TISSUE SPECIFICITY;SUBCELLULAR LOCATION;MASS SPECTROMETRY
      tissue: Saliva.
    14. 14.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] ASN-77
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